Timing for coverage. It is important that the right fielder cover 2B.
Daylight plays. Where SS, 2B, and 3B give a sign to the pitcher to pick a runner off.
Catcher signals. Catcher can drop their glove to tell the pitcher to throw to second.
Catcher can give a signal to step off if the runner is too far of the base.
First-and-third defenses.